General Pharmaceutical Manufacturing
Impact of Uncontrolled Humidity
The importance of quality pharmaceutical products has always been paramount, and the current pandemic has reiterated the necessity of maintaining high standards. To cater to the growing pharmaceutical needs of the population, the industry requires advanced solutions to meet demand while ensuring product quality.
Air quality is crucial in the pharmaceutical industry. The presence of moisture in pharmaceutical plants can deteriorate product quality, cause organic corrosion, biochemical reactions, germination of unwanted microorganisms, and impair product accuracy and uniformity in formulations. Therefore, moisture-free air is essential at every stage of the pharmaceutical process, including processing, manufacturing, storage, research and testing, and packaging.
Additional Effects
Storage
Aluminum’s moisture sensitivity can lead to moisture being packed with the tablet.
Packaging
● Dry Powder and Vial Filling: Moisture causes powder to stick to conveyors, preventing efficient airveying and filling. Dehumidified air is critical for the hygroscopic chemicals in the pharmaceutical industry. Final packaged material must maintain its moisture level to ensure product validity during shelf life.
● Injection Manufacturing: Injections are prepared under sterile conditions, requiring specific humidity levels. Dry Injection processing requires 15±5% RH and a temperature of 21ºC. The filling and sealing operations are critical, requiring precise and dry powder handling to avoid lump formation and stickiness.
● Diagnostic Kit Manufacturing, Storage, and Packaging: Components used in rapid test kits are highly hygroscopic and can react with moisture, leading to inaccurate test results. Maintaining recommended temperature and humidity levels during assembly and manufacturing is essential.
● Nutraceuticals: Nutraceuticals are hygroscopic and require humidity control. Moist environments yield inconsistent products and reduce production rates. For example, Spirulina tablets are processed under strict moisture control to maintain quality.
Recommendation
Ensuring the recommended temperature and humidity parameters is essential for the overall quality of pharmaceutical products. This will guarantee not only visual appeal but also the effectiveness and stability of the medication.
Solution
Why Choose Josem?
Josem Desiccant Dehumidifiers provide the ideal solution for controlling humidity and temperature during the tablet coating process. Our dehumidifiers are specifically designed to meet the stringent requirements of the pharmaceutical Josem Solution
Dehumidification or Moisture/Humidity Control Solutions
Dehumidification is essential across all stages and processes of the pharmaceutical industry, including processing, manufacturing, storage, research and testing, and packaging. Maintaining ideal RH conditions is crucial, and dehumidifiers play a vital role.
Josem Desiccant Dehumidifiers can maintain RH as low as 1% or even lower at a constant level, regardless of ambient conditions during production, processing, storage, and packaging. Josem dehumidifiers are CNC fabricated with a powder-coated finish and incorporate high-performance Metal Silicate Fluted media, which is bacteria-static and non-toxic, making them ideal for meeting GMP requirements of the pharmaceutical industry.
